the ordinary granactive retinoid 2 emulsion ingredients

THE ORDINARY GRANACTIVE RETINOID 2 EMULSION INGREDIENTS SKIN
THE ORDINARY GRANACTIVE RETINOID 2 EMULSION INGREDIENTS PATCH

Regarding anti-aging, there is a pretty recent, Estee Lauder sponsored study that compared the in-vitro (not on real human beings but on skin models) collagen-boosting effectiveness of Hydroxypinacolone Retinoate, tretinoin, good old retinol and retinyl palmitate (RP). Both studies found the formulas effective but they contained other things too, so it's hard to judge how well HPR did. We found two Italian studies both examining the efficacy of HPR combined with other things (retinol in both cases, and papain in one of them) for the treatment of acne. But, before you do, you have to know that the info we have about HPR at the moment is mainly from the manufacturer, whose tests may or may not be accurate or properly designed (such as controlled, double-blind and conducted on an appropriate number of people).Īs HPR is pretty new there isn't that much independent research we could find yet. These results sound sooo promising that we don't blame you if you wanna run out right now and get an HPR formula to slather on your face. Also, there was a 'dramatic reduction of lines and wrinkles' after applying 0.2% HPR around the eyes twice a day for 14 days.

THE ORDINARY GRANACTIVE RETINOID 2 EMULSION INGREDIENTS PATCH

According to the manufacturer's tests, 24 hours of an occlusive patch with 0.5% HPR resulted in significantly lower irritation than 0.5% retinol. The big promise of HPR is that it's similarly active as retinoic acid (no conversion needed, remember) but without the irritation. It binds directly to the retinoid receptors of the skin cells to work its skincare magic. Other forms of retinoids have to be converted by our metabolic machinery to do something. If you've already read our description about retinol or retinyl palmitate, you know that the active ingredient our skin cells can interpret is retinoic acid. It's a so-called retinoic acid ester, meaning that it's directly related to retinoic acid. On balance, the point is this: in contrast to real plant oils, wax esters were designed by Mother Nature to stay on the surface and form a protective, moisturizing barrier and jojoba oil being a wax ester is uniquely excellent at doing that. Third, jojoba oil moisturizes the skin through a unique dual action: on the one hand, it mixes with sebum and forms a thin, non-greasy, semi-occlusive layer on the other hand, it absorbs into the skin through pores and hair follicles then diffuses into the intercellular spaces of the outer layer of the skin to make it soft and supple. has this not fully proven theory that thanks to this, jojoba might be able to 'trick' the skin into thinking it has already produced enough sebum, so it might have 'skin balancing' properties for oily skin. Second, jojoba oil is the most similar to human sebum (both being wax esters), and the two are completely miscible. If you have some pure jojoba oil at home, you should be fine using it for years. (Many plant oils tend to go off pretty quickly). Even if you heat it to 370 C (698 F) for 96 hours, it does not budge. So being a wax ester results in a couple of unique properties: First, jojoba oil is extremely stable.

25-30% of human sebum is also wax esters to give us people environmental protection. Wax esters are on the outer surface of several plant leaves to give them environmental protection.

Chemically, a wax ester is a fatty acid + a fatty alcohol, one long molecule. Mother Nature also created wax esters but for a totally different purpose. Mother Nature created triglycerides to be easily hydrolyzed (be broken down to a glycerin + 3 fatty acid molecules) and oxidized (the fatty acid is broken down into small parts) - this happens basically when we eat fats or oils and our body generates energy from it. The fatty acids attached to the glycerin vary and thus we have many kinds of oils, but they are all triglycerides. So what the heck is a wax ester and why is that important anyway? Well, to understand what a wax ester is, you first have to know that oils are chemically triglycerides: one glycerin + three fatty acids attached to it.

The ordinary granactive retinoid 2 emulsion ingredients